Nature, Količina 420Sir Norman Lockyer Macmillan Journals Limited, 2002 |
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Stran 287
... BRCA2 controls the function of RAD51 , a recombinase enzyme , in pathways for DNA repair by homologous recombination . We report here the structure of a complex between an evolutionarily conserved sequence in BRCA2 ( the BRC repeat ) ...
... BRCA2 controls the function of RAD51 , a recombinase enzyme , in pathways for DNA repair by homologous recombination . We report here the structure of a complex between an evolutionarily conserved sequence in BRCA2 ( the BRC repeat ) ...
Stran 291
... BRCA2 to regulate RAD51 filament formation , we analysed the RAD51- BRCA2 interaction in the context of the crystallographic RecA filament ( Fig . 3a ) 18 . In the crystal , the RecA molecules pack into a helical structure that closely ...
... BRCA2 to regulate RAD51 filament formation , we analysed the RAD51- BRCA2 interaction in the context of the crystallographic RecA filament ( Fig . 3a ) 18 . In the crystal , the RecA molecules pack into a helical structure that closely ...
Stran 293
... BRCA2 ( amino acids 1338-1617 ) was fused at its C terminus to three consensus nuclear localization signals in pEF - Myc - Nuc ( Clontech ) . Constructs were verified by nucleotide sequencing . Observations were made 72-96 h after ...
... BRCA2 ( amino acids 1338-1617 ) was fused at its C terminus to three consensus nuclear localization signals in pEF - Myc - Nuc ( Clontech ) . Constructs were verified by nucleotide sequencing . Observations were made 72-96 h after ...
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