Nature, Količina 429Sir Norman Lockyer Macmillan Journals Limited, 2004 |
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Zadetki 1–3 od 5
Stran 311
... RN - tre . RN - tre exerted a strong inhibition on circular ruffles ( Figs la and 2a ) . A catalytic mutant ( RN - treR150 ) displays no GAP activity on Rab5 , and is inactive in bioassays in which wild - type RN - tre can suppress Rab5 ...
... RN - tre . RN - tre exerted a strong inhibition on circular ruffles ( Figs la and 2a ) . A catalytic mutant ( RN - treR150 ) displays no GAP activity on Rab5 , and is inactive in bioassays in which wild - type RN - tre can suppress Rab5 ...
Stran 312
... RN - tre mutants to inhibit circular ruffling perfectly correlated with their ability to inhibit macropinocytosis ( Fig . 2b ) . Thus , two indepen- dent molecular functions of the RN - tre protein ( that is , the GAP activity and ...
... RN - tre mutants to inhibit circular ruffling perfectly correlated with their ability to inhibit macropinocytosis ( Fig . 2b ) . Thus , two indepen- dent molecular functions of the RN - tre protein ( that is , the GAP activity and ...
Stran 313
... RN - tre and Rab5 . A simple possibility to explain the connections among these three proteins is to postulate that RN - tre is an effector of Rab5 . GAP proteins bind preferentially to the GTP- bound forms of small GTPases , thus ...
... RN - tre and Rab5 . A simple possibility to explain the connections among these three proteins is to postulate that RN - tre is an effector of Rab5 . GAP proteins bind preferentially to the GTP- bound forms of small GTPases , thus ...
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