Nature, Količina 429Sir Norman Lockyer Macmillan Journals Limited, 2004 |
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Zadetki 1–3 od 71
Stran 841
... membrane by the cytosolic p97 ATPase . Here we identify a p97 - interacting membrane protein complex in the mammalian ER that links these two events . The central component of the complex , Derlin - 1 , is a homologue of Der1 , a yeast ...
... membrane by the cytosolic p97 ATPase . Here we identify a p97 - interacting membrane protein complex in the mammalian ER that links these two events . The central component of the complex , Derlin - 1 , is a homologue of Der1 , a yeast ...
Stran 842
... membrane segments with both the amino and carboxy termini in the cytosol ( Fig . 1c ) , consistent with experimental results on yeast Derl ( ref . 22 ) . The smaller p97 - interacting protein does not have identifiable homologues ...
... membrane segments with both the amino and carboxy termini in the cytosol ( Fig . 1c ) , consistent with experimental results on yeast Derl ( ref . 22 ) . The smaller p97 - interacting protein does not have identifiable homologues ...
Stran 846
... Membrane proteins with misfolded cytosolic or intra - membrane domains do not require Derl and might move through a different translocation channel , perhaps the Sec61 channel . Alternatively , they may not need a channel at all , as ...
... Membrane proteins with misfolded cytosolic or intra - membrane domains do not require Derl and might move through a different translocation channel , perhaps the Sec61 channel . Alternatively , they may not need a channel at all , as ...
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