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105A-105B. Navigation and Nautical Astronomy. (3-3) Yr. EINARSSON Tu Th, 11, and one observing period. Prerequisite: Mathematics C. Astronomy as applied to navigation. Use of sextant, chronometer, compass, Nautical Almanac, nautical tables. Determination of time, latitude, and longitude on shipboard by the methods of Marq St. Hilaire, Aquino, and Johnson. Sailings. Great circle sailing. Deviation of the compass.

107. Method of Least Squares. (2) I. M F, 1–4.

EINARSSON

The fundamental principles and processes of the method of least squares and their application to the solution of astronomical, physical,“ and engineering problems.

108. Interpolation. (3) II.

SHANE

Two lectures, one three-hour computing period per week. Prerequisite: a knowledge of differential and integral calculus.

The more useful formulae of interpolation, and their application in the use of astronomical and other tables. Development of the formulae of numerical differentiation and integration and their application in the construction of tables. Practice in extensive numerical computations, with special aim at rapidity and exactness.

110. The Theory of Astronomical Refraction. (2) I.

Two lectures per week. Prerequisite: course 104A-104B.

*112. Eclipses. (3) I.

SHANE

SHANE

Two lectures, one three-hour computing period per week. requisite: course 104A-104B.

114. Practical Astronomy for Engineers. (3) I.

Pre

EINARSSON

Tu Th, 9, and one observing period. Prerequisite for students in the College of Civil Engineering: Astronomy 3 and Civil Engineering 3. The subject matter of course 104A-104в more briefly presented, and adapted to the needs of students of civil engineering. The observatory is open for this course two evenings and one afternoon. The arrangement of the work depends so largely upon weather conditions that the student should reserve for this course several observatory periods. 116. Measurements and Reduction of Astronomical Photographs. (3) II. EINARSSON

Two lectures, one three-hour computing period per week. Prerequisite: course 104A.

117. Astrophysics. (3) II.

Tu Th, 11, and one laboratory period.

MEYER

A general review of present-day problems in astrophysics with particular reference to the application of the spectroscope to their solution. Open to all qualified students.

199. Special Study for Advanced Undergraduates. (1 or 2) Either halfThe STAFF (CRAWFORD in charge)

year.

Investigation of special problems to be selected according to the preparation and the needs of the individual students. Limited to students whose major is astronomy.

* Not to be given 1923-24; to be given 1924-25.

GRADUATE COURSES

Concerning conditions for admission to graduate courses see page 3 of this announcement.

Course 206 is prerequisite to courses 207, 209, 210A-210в, and 212A212B.

206. Theoretical Astronomy. (3) I or II.

LEUSCHNER

Prerequisite: course 1 or 103A; Mathematics 4A-4B or 109; ordinarily also Physics 105A.

207. Theoretical Astronomy. (3) I or II.

LEUSCHNER

The relative accuracy of the various methods of determining preliminary orbits.

208A-208B. Introduction to Celestial Mechanics. (3-3) Yr. M W F, 9.

SHANE, LEUSCHNER

CRAWFORD

209. Special Perturbations. (3) I or II. +*210A-210B. The General Perturbations of the Minor Planets after Hansen, Newcomb, and Hill. (3-3) Yr. +*212A-212B. Satellite Theory and Introduction to the Lunar Theory. (3-3) Yr.

CRAWFORD

CRAWFORD

†213. Selected Topics in Celestial Mechanics. (2) Either half-year. LEUSCHNER 214. Advanced Practical Astronomy. (3) Either half-year. EINARSSON M W, 11; M, 7-10 p.m. Prerequisite: course 104A-104B. 215. Advanced Study and Research. Either half-year. Th, 4-6. Credit by special arrangement. The STAFF (LEUSCHNER in charge)

Critical discussion and review of current astronomical publications. Investigation of special problems to be selected according to the preparation and the needs of individual students.

299. Thesis for the Master's Degree.

LICK OBSERVATORY

The STAFF

The Lick Observatory at Mount Hamilton forms a separate department of the University. The unrivaled facilities for advanced astronomical work which are offered by its fine equipment, in this favorable location, are too well known to require description here. The department is open to graduate students under regulations prescribed by the Regents. The degrees of Master of Arts and Doctor of Philosophy are offered to students who have fulfilled the required conditions. (See Announcement of the Graduate Division.) For information relating to graduate work at the 'Observatory intending students should address the Dean of the Graduate Division at Berkeley, or the Director of the Lick Observatory, at Mount Hamilton, Santa Clara County, California.

*Not to be given 1923-24; to be given 1924-25.

These courses form a series which the student can complete in about three years. One or more of these courses are usually offered every halfyear, the selection being based on the needs and the preparation of the graduate students in astronomy.

BACTERIOLOGY AND EXPERIMENTAL PATHOLOGY

T. D. BECKWITH, Ph.D., Associate Professor of Bacteriology (Chairman of the Department).

IVAN C. HALL, Ph.D., Associate Professor of Bacteriology.

RUTH L. STONE, Ph.D., Instructor in Bacteriology.

W. W. REICH, M.A., Assistant in Bacteriology.

A. J. SALLE, B.S., Research Assistant in Bacteriology.

LEWIS F. MORRISON, M.A., Edith J. Claypole Fellow in Pathology.

Preparation for the Major.-Required: Bacteriology 1; Chemistry la; Zoology la; Physics 2A-2B; French or German. Recommended: Chemistry 1B, 8, 9; Botany 2A, 2B.

The Major. Required minimum: Bacteriology 101 (8), and either 199 (3) or 103 (3), and 13 units including related subjects, as for example, certain courses in hygiene, zoology, biochemistry, or entomology.

Honors Students.-Honors will be recommended for candidates who present high grade performance in at least the minimum for the major in bacteriology and in other biological subjects.

LOWER DIVISION COURSE

1. General Bacteriology and Microbiology. (4) II.

HALL, STONE, REICH, and Student Assistants

Lectures, Tu Th, 9; laboratory, Sec. 1, M W F, 9-11; Sec. 2, M W F, 1-3, Tu Th S, 10-12. Weekly quiz to be arranged. Prerequisite: Chemistry 1A or high school chemistry and Physiology 1. Fee, $10. Deposit $5, subject to refund, less deduction for breakage at end of half-year.

Early history of bacteriology; sterilization; preparation of culture mediums; relationships among micro-organisms, bacteria, yeasts, molds, protozoa and filterable viruses; microscopic examination and cultivation of bacteria; effect of physical and chemical agencies on bacteria; biochemical activities—fermentation, putrefaction; isolation of pure cultures; identification of species; introduction to bacteriology of air, soil, sewage, water, milk and its products, other foods, industrial processes, and certain human, animal, and plant diseases.

UPPER DIVISION COURSES

The upper division courses are open only to such academic students as have attained a thoroughly satisfactory grade in the preceding courses in this department.

101. Microorganisms in their Relation to Disease. (8) I.

BECKWITH, HALL, STONE, REICH Lectures, M Tu Th F, 1; laboratory, M Tu Th F, 2-5. Fee and deposit for non-medical students: fee, $10; breakage and material, $10, subject to refund less deduction at end of half-year.

The comparative etiology of disease with particular study of its agents, the pathogenic bacteria and protozoa. Consists of work dealing with cultural methods, infection, immunity, and experimental pathology. Required of all medical students. May be taken also by a few selected non-medical students.

103. Anaerobic Bacteriology. (3) II. M W, 9-12; F, 8-11.

HALL

Prerequisite: Bacteriology 101 with grade of A or B. Laboratory, assigned reading, and informal conferences. Historical; practical methods of isolation, culture, and study of the obligately anaerobic bacteria; study of the diseases caused by them and industrial processes in which they are concerned; introduction to undergraduate and graduate research in special problems of anaerobic bacteriology.

199. Special Study for Advanced Undergraduates.

year.

(3-5) Either halfHALL in charge Undergraduate research problems. Open to qualified students by special arrangement with any professor or instructor in the staff.

GRADUATE COURSES

Concerning conditions for admission to graduate courses see page 3 of

this announcement.

201. Research in Problems of Bacteriology, Infection, Immunity, and Experimental Pathology. Either half-year.

205. Seminar. No credit.

The STAFF (BECKWITH in charge)

The STAFF (BECKWITH in charge)

BIOCHEMISTRY AND PHARMACOLOGY

CARL L. A. SCHMIDT, Ph.D., Associate Professor of Biochemistry (Chairman of the Department).

EDWARD S. SUNDSTROEM, M.D., Assistant Professor of Biochemistry.
GUY W. CLARK, Ph.D., Assistant Professor of Pharmacology.

GOODWIN LEB. FOSTER, Ph.D., Assistant Professor of Biochemistry.
DAVID M. GREENBERG, B.S., Associate in Biochemistry.

JAMES L. BRAKEFIELD, M.A., Assistant in Biochemistry.

C. M. MCCAY, M.S., Assistant in Biochemistry.

EUGENE S. MÁY, M.D., Assistant in Pharmacology.

Preparation for the Major.—Required: matriculation physics, Chemistry 1A-1B, 8, and Zoology 1A, 1B or Physiology 1. Recommended: Chemistry 5, 9; reading knowledge of French or German.

The Major.-Choice may be made of one of the following groups:
(a) Biochemistry 101 (9), 110 (4), 112 (1), 199 (9).

(b) Biochemistry 101 (9), 110 (5), Physiology 101 (10), or 100A-100в (8) and 2 units physiology or biochemistry.

(c) Biochemistry 101 (9), 110 (10), 112 (1), 199 (3).

(d) Biochemistry 101 (9), at least 6 additional units of biochemistry as indicated above, and not more than 9 units from the following: Chemistry 5 or 6A-6B, 100, 110, 120; Botany 111; Bacteriology 101, 103; Zoology 103, 106A-106в, 107, 109, 112, 114; Anatomy 101, 102, 105; Household Science 102, 106, 120A-120в. Other courses may be substituted in exceptional cases.

For medical students the prerequisites are as prescribed for the Medical School. Courses 101 and 102м are required.

The attention of intending advanced students in biochemistry is called to the fact that modern developments in this field call increasingly for a good knowledge of physical chemistry, quantitative chemical methods and the ability to read French and German scientific literature.

UPPER DIVISION COURSES

Matriculation physics, Chemistry 1A-1B, 8, and Zoology 1A and 1B, or Physiology 1 are prerequisite to courses 101 and 103.

101. Biochemistry. (9) II.

SCHMIDT, SUNDSTROEM, FOSTER, and Assistants. Lectures, M Tu W Th 1, F, 9; laboratory, M Tu W Th, 2-5. For fees charged medical students see Medical School Announcement. The lectures in this course consist of a brief discussion of the physico-chemical basis of life processes, a survey of those classes of substances which are to be found in animals and plants, a discussion of the changes which these substances undergo during life and during utilization as food, and a general survey of the field of nutrition and energy exchange.

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