(c) Freehand Drawing. (d) Arithmetic. Fundamental rules; fractions; common and deci (e) Algebra, to quadratics with one unknown quantity. (g) Geometry. Elementary, including mensuration of solids. An applicant who fails to pass the entrance examination may be conditioned in not more than two subjects, in which he will be re-examined after three months. Should he again fail, his fees will be refunded, except that the sum of twenty-five dollars will be retained, which will be placed to his credit if he should return to the college and pay the balance of his fees within two years. Applicants who desire to be matriculated without examination for the course leading to the degree of Graduate in Pharmacy may present their credentials to the dean at any time before the opening of the college on September 1, 1915. All others will present themselves for examination at the college on Wednesday, September 1, at 9 a.m. B. FOR THE DEGREES OF PHARMACEUTICAL CHEMIST (PH.C.) AND Applicants will be matriculated who have received a degree in Letters or Science, or who have been matriculated in the University of California, or who present a diploma from an accredited high school or other institution whose credentials will be accepted for entrance to the College of Letters and Science of the University. Such diplomas or credentials should be presented to the Dean before August 10, 1915. Those who cannot present such credentials are required to take the entrance examinations at Berkeley. Applications by mail for examination permits should be sent to the Recorder of the Faculties at Berkeley. These permits must be secured in advance. Matriculation examinations at Berkeley will be held on August 5, 6, 7, 9, 10, 1915. The examinations will be prepared and conducted by such officers as may be appointed by the departments. COURSES OF INSTRUCTION, 1915-1916 CHEMISTRY FIRST OR JUNIOR YEAR Inorganic and Didactic. Professor GREEN. The course of instruction begins with the phenomena of changes, physical and chemical. The lectures are followed by experiments on the part of the student in the laboratory, illustrating the principles and facts spoken of. Theory is considered when the student lays the foundation of simple chemical knowledge through experiments which he is taught to carry out. The construction of chemical formulae is then dwelt upon, and is followed by stoichiometry. In the course of study, the groups typified by the elements hydrogen, oxygen, nitrogen, chlorin, and carbon are described, with their compounds. Then follows the chemistry of the metals, with their oxides and salts. They are taken up in the order of their analytical classification, with this exception, that the alkalies and the alkali earths are mentioned first. The chemistry of inorganic materia medica is made a feature. Organic and Didactic. SECOND OR SENIOR YEAR Professor GREEN. This course in organic chemistry consists of a series of lectures, together with laboratory work. The subjects are the aliphatic hydrocarbons of the paraffin, olefine, and the acetylene series. Also the derivatives of the open-chain hydrocarbons, viz., the halogen derivatives, alcohols, ethers, sulphuric compounds, aldehyds, ketones, acids, esters, amins, amids, carbohydrates, carbonic acid, and cyanogen derivatives. The course is continued so as to include the cyclic hydrocarbons and derivatives. These comprise the phenols, cresols, diatomic phenols, likewise the aromatic aldehyds, ketones, and acids; in fact, cyclic compounds of pharmaceutical interest claim the greatest attention. The organic bodies containing nitrogen are then considered, especially the alkaloids. This course includes the study and classification of the modern synthetic remedies. CHEMICAL LABORATORY FIRST OR JUNIOR YEAR Experimental. Professor GREEN. The course begins with examples of chemical action, followed by the analysis and synthesis of simple things. The chemistry of the gases follows, the student isolating oxygen, hydrogen, nitrogen, chlorin, and experimenting with their compounds. Then the non-metals are considered and their properties investigated. The theory of the manufacture of salts and acids used in pharmacy, with their doses, follows, together with identification of the official acids, oxides, metals and salts. This completes the first part of the junior year. Then the properties of the metals are shown by reagents, together with the behavior of the acids, from the first steps leading to the study of analytical chemistry. Qualitative analysis, based on the tests in the United States Pharmacopoeia, completes the term. In adopting such a wide range of study it is the aim to have typical processes of precipitation, neutralization, crystallization, and analysis carefully and correctly performed, rather than compel the student to do hurried work. SECOND OR SENIOR YEAR Professor GREEN. Analytical and Experimental. The course commences with elementary crystallography and the recognition of each system, with examples chosen from official salts. Models, both opaque and transparent, are used as aids. Then follows a short laboratory course in organic chemistry. The work is intended to elucidate classes and types. The student then begins analytical work which embraces a systematic course of quantitative chemical analysis, volumetric, gravimetric, and colorimetric. This is a necessity in the education of a practical pharmacist, and the course is shaped to this end. Quantitative (gravimetric) chemical analysis and manipulation, and volumetric analysis and its application to practical pharmacy, complete the first senior session. The polariscope is employed in estimating sugar, also in determining the optical rotation of the essential oils. The absorption bands of coloring matter are demonstrated by means of the spectroscope. Along with these physical tests, the methods for the determination of the melting points are studied, with examples, such as melting point of petrolatum, cacao butter, lard, the waxes, salol, naphthaline, and acetanilid. chemical tests for the new official synthetic compounds, as well as some in frequent use that are not recognized by the United States Pharmacopoeia, are carried out not alone as to identity, but also with a view to the detection of impurities. The Qualitative and quantitative analysis of the urine is then studied. The course concludes with experimental work in the identification and separation of poisons under conditions similar to those found in cases of accidental or criminal poisoning. This constitutes the chemical side of toxicology. THEORY AND PRACTICE OF PHARMACY FIRST OR JUNIOR YEAR Professors NISH and SIMMONS. Didactic and Operative. Theoretical pharmacy is taught by lectures and reviews explanatory of the operations and processes employed in laboratory work, while operative pharmacy is taught by requiring the student to perform the operations himself under supervision. The course begins with lectures on elementary pharmacy, the laboratory work beginning with the simpler pharmaceutical processes, the operations being first explained in the lecture room. By teaching theoretical and practical pharmacy simultaneously, as far as possible, both are better understood and their study made more interesting. Beginning with a notice of the pharmacopoeias of Western nations, the systems of weights and measures used by them, and the apparatus employed for weighing and measuring, the student passes on to the subject of specific gravity and the methods of estimating the same. Then follows a consideration of the application of heat to pharmacy, and of the measurement of heat by different thermometers. After this the simpler operations of pharmacy are taken up, such as solution, evaporation, distillation, sublimation, precipitation, filtration, dialysis, crystallization, etc. Comminution is then explained-slicing, bruising, grinding, and pulverizing, in mills, in mortars, and by other means; also sifting, elutriation, filtration, clarification, and decoloration. The various processes of extraction employed in pharmacy are then considered, such as infusion, decoction, maceration, digestion, percolation or displacement, repercolation, expression, etc. Then the practical operation of these processes is shown in the preparation of the official waters, syrups, infusions, decoctions, tinctures, followed by mixtures, emulsions, ointments, cerates, oleates, etc. The manufacture of suppositories, pills, triturates, troches, and efferescing granular salts concludes the work of the year. Identification. During the term practical work is given in the identification of pharmaceutical preparations, manufactured by the students in the laboratory. Didactic and Operative. SECOND OR SENIOR YEAR Professors NISH and SIMMONS. The senior course is a continuation of the work begun in the junior year, but gradually leads on to operations requiring more skill and care. It includes lectures and reviews, followed by laboratory work on the manufacture of chemical syrups, the official liquors, solid and fluid extracts, scale salts, spirits, resins, glucosides, alkaloids, etc., so that when the course is completed, the student has made one or more or almost every type of preparation in the United States Pharmacopoeia and National Formulary. As this work proceeds, the processes of percolation, distillation, etc., are operated by the students, and each process is explained. The student is required to know the reason for every detail of each process. The menstrua employed in galenical preparations being dependent upon the chemical constituents contained in the drugs operated upon, this course forms a complement with that on organic materia medica and pharmacognosy. The pharmacy of the new synthetic remedies receives due attention. In the lectures on pharmacy is included a consideration of the inorganic materia medica, so that nearly all the official drugs and preparations in the pharmacopoeia are noticed, and the student is instructed in the nature, preparation, and uses of practically all the more important official drugs, chemicals and medicants. Assay Work.-Several laboratory sessions are devoted to the processes of assaying. Students are required to make gasometric estimations of solutions of hydrogen dioxide and of spirit of nitrous ether; also alkaloidal assays of such drugs as opium, cinchona, nux vomica, belladonna, hydrastis, etc. Commercial samples of pepsin and pancreatin are estimated to determine their active valuation. The work of preparing some of the standard toilet articles, with the capping and wrapping of the containers, is carried out in the laboratory. Prescription Work.-The course includes about twelve lectures as well as the actual dispensing of prescriptions. These deal with all the details of the management of the prescription counter, the subject of incom patabilities being fully considered. Many difficult or obscure prescriptions are submitted to the students, who are called upon to deal with them as they deem best. Their knowledge of weighing, measures, percentages, doses, etc., as well as their skill in compounding, are tested by this work in the laboratory. Identification. During the term practical work is given in the identification of pharmaceutical preparations, manufactured by the students in the laboratory. |