Chemical Carcinogens, 2. del

activity adduct administration AFB₁ AFB2 aflatoxin agents alkylating agents alkylation amines animals Biochem bracken Cancer Inst Cancer Lett Cancer Res Carcinogenesis carcinogenic carcinoma cells Chem Chem.-Biol chemical chromatin colon concentrations contained derivatives detected diet DMBA DNA synthesis dose effects enzyme esophagus experimental exposure Fischer Food Cosmet forestomach formation Gann genotoxic hamster hepatic human IARC increased induced inhibition inhibitors injection Interact intestine JNCI kidney Krebsforsch levels Lijinsky liver DNA liver microsomes liver tumors lung mammary mammary gland metabolism metabolites methyl mg/kg mice microsomes mouse skin mutagenic Mutat Mycotoxins N-nitroso nasal cavity Natl Nature London NDEA NDMA nitrite nitrosamines nitroso compounds O=NN rat oral Pharmacol potential Preussmann Proc protein quercetin rat liver reaction reduced reported samples Schmähl species studies subcutis T-2 toxin tissue toxic Toxicol toxin treatment triazene tumor promotion urinary bladder vitro vivo µg/kg