Nature, Količina 450Sir Norman Lockyer Macmillan Journals Limited, 2007 |
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Stran 300
... mRNA stability and Roquin's localization to cytoplasmic stress granules ' , from which some mRNAs are transported to processing bodies where mRNA degradation occurs16 , we next asked if ICOS mRNA is localized to stress granules and if ...
... mRNA stability and Roquin's localization to cytoplasmic stress granules ' , from which some mRNAs are transported to processing bodies where mRNA degradation occurs16 , we next asked if ICOS mRNA is localized to stress granules and if ...
Stran 301
... mRNA levels Supplementary Fig . 11 ) . It is thus possible that several miRNAs ct together regulate Icos mRNA decay . We next asked whether defective miR - 101 - mediated repression could explain increased expression of other genes in ...
... mRNA levels Supplementary Fig . 11 ) . It is thus possible that several miRNAs ct together regulate Icos mRNA decay . We next asked whether defective miR - 101 - mediated repression could explain increased expression of other genes in ...
Stran 302
... mRNA ( % ) t1 / 2 = 1.3 h ΚΟΙ KH T 0 * 1 / 2 = 0.6 h T 0 0.5 1 1.5 2 2.5 3 Time after actinomycin D treatment ( h ) 3 ' UTR - F3 Wild - type Roquin ( M199R ) Roquin ** ** ** b Hi Low Ni Hi Low Ni Hi Low Ni GFP ( Roquin ) Hi GFP Nil Hi I ...
... mRNA ( % ) t1 / 2 = 1.3 h ΚΟΙ KH T 0 * 1 / 2 = 0.6 h T 0 0.5 1 1.5 2 2.5 3 Time after actinomycin D treatment ( h ) 3 ' UTR - F3 Wild - type Roquin ( M199R ) Roquin ** ** ** b Hi Low Ni Hi Low Ni Hi Low Ni GFP ( Roquin ) Hi GFP Nil Hi I ...
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activity analysis applications atoms Avr3a behaviour Biol brain Caenorhabditis elegans Cancer candidates carbon catalysts cavity Cell Biology Center changes chromosome climate conservation Department disease Drosophila melanogaster dynamics elegans emissions energy evolution evolutionary experience function gene expression genetic genome global human ICOS imaging indicated Institute interactions JHDM1B Jhdm2a laboratory levels male-biased expression mechanisms Medical methods mice microRNA miRNA molecular molecules motifs mouse mRNA mutant Nature Nature Publishing Group NATUREJOBS neural neurons Neurosci odour olefin metathesis optical organ orthologues pathway Phys piRNA Piwi position postdoctoral predicted protein protein-coding receptor region regulation response role Roquin says Science scientific scientists sequence signal SNMP solar wind species spermatids structure Supplementary Fig Supplementary Information Supplementary Table target Technology tion tissue transcription transgene University wild-type wtrw X chromosome