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The subject matter covered by the entrance examinations in the California College of Pharmacy is as follows:

English.-Reading and writing English correctly, giving attention to composition rather than to grammar, as we care little for the technical grammar. Text-book-California State Series Advanced Grammar.

Geography.-Physical rather than political geography, giving attention to the physical features of the continents and their effects upon the climate, and consequently, upon the vegetable and the animal life. Textbook--California State Series Advanced Geography.

Drawing.-The ability to draw simple objects, as chair, book, box, leafy branch of a tree, or leaf, etc. No book required.

Arithmetic.—The announcement speaks fully on this subject. Proportion, percentage, fractions, and metric as well as English systems are of special importance. Text-book--California State Series Advanced Arithmetic.

Algebra.--The four fundamental operations, addition, subtraction, multiplication and division, together with factoring and fractions. Textbook-Wentworth’s Algebra. Latin.—The announcement speaks fully on this subject.

Any ele mentary Latin book.

Geometry. The measurement of lines, angles, surfaces and solids. Usually given under the heading of “Mensuration.'' Text-book-California State Series Advanced Arithmetic, or any other Advanced Arithmetic.

A condition could be carried in any two of the above named subjects, said condition to be removed during the first year.

An applicant who fails to pass the entrance examination may be conditioned in not more than two subjects, in which he will be re-examined after three months. Should be again fail, his fees will be refunded, except that the sum of twenty-five dollars will be retained, which will be placed to his credit if he should return to the college and pay the balance of his fees within two years.

Applicants who desire to be matriculated without examination for the course leading to the degree of Graduate in Pharmacy may present their credentials to the dean at any time before the opening of the college on September 24, 1918. All others will present themselves for examination at the college on Saturday, September 24, at 9 a.m.

Beginning with the college year 1922–23, the minimum entrance requirement will be graduation from an accredited high school, or the educational equivalent. This is to meet the requirements adopted by the American Conference of Pharmaceutical Faculties.

B. FOR THE DEGREES OF PHARMACEUTICAL CHEMIST (PH.C.) AND

BACHELOR OF PHARMACY (PHAR.B.) Applicants will be matriculated who have received a degree in Letters or Science, or who have been matriculated in the University of California, or who present a diploma from an accredited high school or other institution whose credentials will be accepted for entrance to the College of Letters and Science of the University. Such diplomas or credentials should be presented to the Dean before September 7, 1918. Those who cannot present such credentials are required to take the entrance examinations at Berkeley. Applications by mail for examination permits should be sent to the Recorder of the Faculties at Berkeley. These permits must be secured in advance.

Matriculation examinations at Berkeley will be held from Thursday, September 19, to Tuesday, September 24, 1918.

The examinations will be prepared and conducted by such officers as may be appointed by the departments.

COURSES OF INSTRUCTION, 1918-1919

CHEMISTRY

FIRST YEAR Inorganic and Didactic.

Professor GREEX. The course of instruction begins with the phenomena of changes, physical and chemical. The lectures are followed by experiments by the student in the laboratory, illustrating the principles and facts spoken of.

Theory is considered when the student lays the foundation of simple chemical knowledge through experiments which he is taught to carry out. The construction of chemical formulae is then dwelt upon, and is followed by stoichiometry. In the course of study, the groups typified by the elements hydrogen, oxygen, nitrogen, chlorin, and carbon are described, with their compounds. Then follows the chemistry of the metals, with their oxides and salts. They are taken up in the order of their analytical classification, with this exception, that the alkalies and the alkali earths are mentioned first. The chemistry of inorganic materia meilica is made a feature.

SECOND YEAR

Organic and Didactic.

Professor GREEN. This course in organic chemistry consists of a series of lectures, together with laboratory work. The subjects are the aliphatic hydrocarbons of the paraffin, olefine, and the acetylene series.

Also the derivatives of the open-chain hydrocarbons, viz., the halogen derivatives, alcohols, ethers, sulphur derivatives, aldehyds, ketones, acids, esters, amins, amids, carbohydrates, carbonic acid, and cyanogen derivatives.

The course is continued so as to include the cyclic hydrocarbons anil derivatives. These comprise the phenols, eresols, diatomie phenols, likewise the aromatic aldehyds, ketones, and acids; in fact, cyclic compounds of pharmaceutical interest claim the greatest attention. The organic bodies containing nitrogen are then considered, especially the alkaloidls.

This course includes the study and classification of the modern synthetie remedies.

CHEMICAL LABORATORY

FIRST YEAR Experimental.

Professor GREEN. The course begins with examples of chemical action, followed by the analysis and sythesis of simple things. The chemistry of the gases follows, the student isolating oxygen, hydrogen, nitrogen, chlorin, and experimenting with their compounds. Then the non-metals are considered and their properties investigated. The theory of the manufacture of salts and acids used in pharmacy, with their doses, follows, together with identification of the official acids, oxides, metals and salts. This completes the first part of the junior year. Then the properties of the cations are shown by reagents, together with the behavior of the anions thus leading to the study of analytical chemistry.

Qualitative analysis, based on the tests in the United States Pharmacopoeia, completes the term. In adopting such a wide range of study it is the aim to have typical processes of precipitation, neutralization, crystallization, and analysis carefully and correctly performed, rather than compel the student to do hurried work.

SECOND YEAR

Analytical and Experimental.

Professor GREEN. The course commences with elementary crystallography and the recognition of each system, with examples chosen from official salts. Models, both opaque and transparent, are used as aids. Then follows a short laboratory course in organic chemistry. The work is intended to elucidate classes and types. The student then begins analytical work which embraces a systematic course of quantitative chemical analysis, volumetric, gravimetric, and colorimetric. This is a necessity in the education of a practical pharmacist, and the course is shaped to this end. Quantitative (gravimetric) chemical analysis and manipulation, and volumetric analysis and its application to practical pharmacy, complete the first senior session.

The polariscope is employed in estimating sugar, also in determining the optical rotation of the essential oils. The absorption bands of coloring matter are demonstrated by means of the spectroscope. Along with these physical tests, the methods for the determination of the melting points are studied, with examples, such as melting point of petrolatum, cacao butter, lard, the waxes, salol, naphthaline, and acetanilid. The chemical tests for the new official synthetic compoun«ls, as well as some in frequent use that are not recognized by the United States Pharmacopoeia, are carried out not alone as to identity, but also with a view to the detection of impurities.

Qualitative and quantitative analysis of the urine is then studied.

The course concludes with experimental work in the identification and separation of poisons. This constitutes the chemical side of toxicology.

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THEORY AND PRACTICE OF PHARMACY

FIRST YEAR

Didactic and Cperative.

Professors Nish and SIMMONS. Theoretical pharmacy is taught by lectures and reviews explanatory of the operations and processes employed in laboratory work, while operative pharmacy is taught by requiring the student to perform the operations himself under supervision. The course begins with lectures on elementary pharmacy, the laboratory work beginning with the simpler pharmaceutical processes, the operations being first explained in the lecture room. By teaching theoretical and practical pharmacy simultaneously, as far as possible, both are better understood and their study made more interesting.

Beginning with a notice of the pharmacopoeias of Western nations, the systems of weights and measures used by them, and the apparatus employed for weighing and measuring, the student passes on to the subject of specific gravity and the methods of estimating the same. Then follows a consideration of the application of heat to pharmacy, and of the measurement of heat by different thermometers. After this the simpler operations of pharmacy are taken up, such as solution, evaporation, distillation, sublimation, precipitation, filtration, dialysis, crystallization, etc. Comminution is then explained-slicing, bruising, grinding, and pulverizing, in mills, in mortars, and by other means; also sifting, elutriation, filtration, clarification, and decoloration.

The various processes of extraction employed in pharmacy are then considered, such as infusion, decoction, maceration, digestion, percolation or displacement, repercolation, expression, etc. Then the practical operation of these processes is shown in the preparation of the official waters, syrups, infusions, decoctions, tinctures, followed by mixtures, emulsions, ointments, cerates, oleates, etc. The manufacture of suppositories, pills, triturates, troches, and efferveseing granular salts concludes the work of

the year.

Identification. During the term practical work is given in the identification of pharmaceutical preparations, manufactured by the students in the laboratory.

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