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SECOND YEAR

Didactic and Operative.

Professors NISH and SIMMONS. The senior course is a continuation of the work begun in the junior year, but gradually leads on to operations requiring more skill and care. It includes lectures and reviews, followed by laboratory work on the manufacture of chemical syrups, the official liquors, solid and fluid extracts, scale salts, spirits, resins, glucosides, alkaloids, etc., so that when the course is completed, the student has made one or more of almost every type of preparation in the United States Pharmacopoeia and National Formulary.

As this work proceeds, the processes of percolation, distillation, etc., are operated by the students, and each process is explained. The student is required to know the reason for every detail of each process. The menstrua employed in galenical preparations being dependent upon the chemical constituents contained in the drugs operated upon, this course forms a complement with that on organic materia medica and pharmacognosy.

The pharmacy of the new synthetic remedies receives due attention. In the lectures on pharmacy is included a consideration of the inorganic materia medica, so that nearly all the official drugs and preparations in the pharmacopoeia are noticed, and the student is instructed as to the nature, the preparations, and the uses of practically all the more important official drugs, chemicals and medicants.

Assay Work. Several laboratory sessions are devoted to the processes of assaying. Students are required to make gasometric estimations of solutions of hydrogen dioxide and of spirit of nitrous ether; also alkaloidal assays of such drugs as opium, cinchona, nux vomica, belladonna, hydrastis, etc. Commercial samples of pepsin and pancreatin are estimated to determine their active valuation.

The work of preparing some of the standard toilet articles, with the capping and wrapping of the containers, is carried out in the laboratory.

Prescription Work. The course includes about twelve lectures as well as the actual dispensing of prescriptions. These deal with all the details of the management of the prescription counter, the subject of incompatibilities being fully considered. Many difficult or obscure prescriptions are submitted to the students, who are called upon to deal with them as they deem best. Their knowledge of weighing, measures, percentages, doses, etc., as well as their skill in compounding, is tested by this work in the laboratory.

Identification. During the term practical work is given in the identification of pharmaceutical preparations, manufactured by the students in the laboratory.

BOTANY AND MATERIA MEDICA

FIRST YEAR

Courses 1 and 4 are continuous lecture and recitation courses during Courses 2, 3, and 4 are continuous laboratory courses

the first year.

during the first year.

1. General Botany and Taxonomy.

Professor CAREY.

A course of lectures on the domains of botany, referring especially to the cell and cell-contents; general morphology, and physiology of cells, tissues, and organs; the absorption, assimilation, and storing of foodsubstances; occurrence and formation of cell-contents; ascent of cellsap; phyto-syntax; symbosis; movements of plants; pollination and fertilization of plants; origin of domestic plants; influence of cultivation, etc.

This course is supplemented by field excursions for the purpose of studying the local flora, especially from the ecological and economic standpoint. Each student is required to analyze a number of flowering and fruiting plants. Special attention is given to taxonomy.

The course also includes lectures and recitations on the gross structure of plant organs, special attention being given to leaf-modification, phyllotaxy, inflorescence, flowers, fruits and seeds. The principles of classification and nomenclature are explained. This course is intended to prepare the student for an intelligent study of the gross structure of vegetable drugs and the identification and classification of the more common plant forms.

2. Microscopy.

Professor CAREY.

Study of the optical properties of mirrors and lenses, and the mechanism and manipulation of the compound microscope; comparison of the more important microscopes now in use; the properties and uses of microreagents; the cutting of sections and preparation of microscopic mounts. This course is a necessary preparation for courses 3 and 4.

3. The Histology of the Cryptogams.

Professor CAREY.

Laboratory course in the study of the histology of types of cryptogamous plants, as algae, fungi, lichnes, liverworts, mosses, and fern. Special attention is given to the evolution and biological relationship of the plant groups referred to as revealed by their structure. The evolution and modification of cells, cell-contents, tissues, and organs; alterations of generations and spore-formation are also considered.

4. The Histology of the Phanerogams.

Professor CAREY.

The laboratory course is a continuation of course 3, and consists of the study of the histology of coniferous, monocotyledonous, and docotyledonous plants. Special attention is next given to cell-modification and cell content, so as to prepare the student for the intelligent study of the histology of vegetable drugs. Suitable micro-chemical reagents are employed to aid in differentiating cells, tissues, and cell-contents. 5. Pharmaceutical Botany.

Professor SCHNEIDER.

A course of lectures on the history and commerce of vegetable drugs, the range, occurrence and distribution of drug-yielding plants with their special morphological characteristics and constituents, etc. A special study of the cultivation of drug-yielding plants in California. What drug-yielding plants may be cultivated profitable in the various geographic areas of the United States, etc. This course form the connecting link between the courses in botany and in pharmacognosy.

6. Materia Medica.

Professors CAREY and SIMMONS. Lectures and recitations on the history, character, gross structure and properties of drugs. Two sessions each week.

One hour a week will be deovted to materia medica following the classification of organic drugs by the natural orders.

PHYSIOLOGY AND FIRST AID

7. Human Anatomy and Physiology.

Professor CAREY.

Lectures and recitations intended to acquaint the student sufficiently with the morphology and physiology of the human body, to enable him to understand the processes of digestion, assimilation, circulation, respiration, and nerve action, and the physiological action of drugs.

8. First Aid and Military Hygiene.

DR. KRUSE.

(a) Instruction and demonstration in first aid. Treatment for injuries and emergencies. One hour a week.

(b) Drill in the transportation of wounded, injured and sick. One hour a week.

(c) Lectures and recitations including the principles of hygiene and sanitation with special reference to personal hygiene, physical training, preventable diseases, clothing, water supply, food and its preparation, the sanitation of dwellings and ships, the disposal of wastes, conditions peculiar to tropic and arctic zones, the hygiene and sanitation of marchers, camps, and battlefields, and the organization and function of the Medical Corps of the United States Army. One hour a week.

(d) Instructions in the duties of a pharmacist in the Medical Corps of the United States Army. One hour a week.

9. Materia Medica.

MATERIA MEDICA

SECOND YEAR

Professor CAREY.

Lectures and recitations on the nomenclature, natural order, botanic source, part official, habitat, constituents, official preparations, properties, action, and uses of drugs, and the doses of their preparations. In this course not only all the official drugs and their preparations but the newer ones will be considered, the physiological action being especially emphasized. The student in actual practice handles the newer drugs of value long before they receive official recognition; hence the reason for acquainting him with these. As far as possible the newer drugs will be exhibited in class work. Two hours a week.

10. Materia Medica Review.

Professor SIMMONS.

One hour a week will be devoted to materia medica following the classification of organic drugs by the natural orders. This is accomplished by the demonstrations with samples of crude drugs for macroscopic study. The features of this course are classification, together with a knowledge of constituents and use in pharmaceutical practice.

PHARMACOGNOSY AND BACTERIOLOGY

SECOND YEAR

1. Pharmacognosy.

Professor SCHNEIDER.

This course consists of the macroscopical and microscopical study of the more important official and unofficial vegetable and animal drugs. Attention is given to the history of drugs; the habitat and range of drugyielding plants and their botanical characters, together with the char acteritsics of the order to which they belong; active and inert constituents; the influence of cultivation on the properties of drugs; the common drug adulterants, the macroscopical and microscopical study of powdered drugs and spices, with special reference to the detection of adulterants, and the identification and comparison of pure and adulterated products; the modes of collecting, manner of curing, garbling, powdering, sifting, and preserving drugs; drug parasites; causes which lead to the deterioration of drugs; drug sophistication, accidental and crimminal; relationship of active and inert drug constituents to methods of extrac tion; the influence of cultivation on the properties and physiological action of drugs; time of collecting.

2. Bacteriology.

Professor SCHNEIDER.

This course consists of lectures, recitations, and laboratory demonstrations. It will include a discussion of the occurrence, range, and distribution, the morphology and physiology of microbes; microbes in health and disease; the use of microbes in the various industries; disinfectants and disinfection; immunity, natural and acquired; phagocytosis, opsonins, toxins, bacterins (vaccines), tuberculins, phylacogens, sanitation, etc. The course is intended to give the student a general view of the subject with special reference to its bearings upon pharmaceutical practice. It is also a preparatory course to the work of the third or graduate year.

TOXICOLOGY

Professor HADYN M. SIMMONS

This course consists of lectures and recitations. It includes the history of toxicology, with definitions of terms, and a sketch of the field of usefulness of this subject to the pharmacist. The influences of habit, tolerance, and idiosyncrasy are fully considered.

Particular attention is given to dosage, medicinal, toxic, and lethal. Also absorption, elimination, and cumulative actions of poisonous substances. The signs and symptoms of poisons are studied in each case, and antidotes and medical treatment receive attention.

Text-book: Brundage's Toxicology.

PHARMACAL JURISPRUDENCE

Mr. H. R. WILEY

Preliminary Course.

This is to prepare students to understand the law as applied to pharmacy.

History and development of the law; Constitution of the United States; The State Constitution; federal law and state law in their relation to each other; definitions. 2 lectures.

Principles of the Law Applied to Pharmacy.

This course deals with the broad responsibility and liability of the pharmacist under the general principles of the law. Its purpose is to acquaint him with his risks as well as his rights, that he may minimize the one and more fully enjoy the other.

The origin, history and scope of pharmacal jurisprudence; the nature of contracts, and the implied contract of guaranty on the part of the pharmacist; liability for negligence (ease law); liability for error (case law); liability of manufacturing pharmacist (case law); contributory

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