NatureSir Norman Lockyer Macmillan Journals Limited, 2007 |
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Zadetki 1–3 od 65
Stran 163
... substrate analogue , adenosine - 5 ′ - [ ( α , β ) -methyleno ] -triphosphate ( AMPcPP ) , and with AMPcPP plus the inhibitor streptolydigin . In the EC / AMPcPP structure , the substrate binds to the active ( ' insertion ' ) site ...
... substrate analogue , adenosine - 5 ′ - [ ( α , β ) -methyleno ] -triphosphate ( AMPcPP ) , and with AMPcPP plus the inhibitor streptolydigin . In the EC / AMPcPP structure , the substrate binds to the active ( ' insertion ' ) site ...
Stran 165
... substrate phosphates is stabilized through 11 hydrogen bonds with six basic residues , among which four were predicted from the yeast EC structures and modelling of the bacterial substrate complex ' ; the other two , Arg ẞ ' 1239 and ...
... substrate phosphates is stabilized through 11 hydrogen bonds with six basic residues , among which four were predicted from the yeast EC structures and modelling of the bacterial substrate complex ' ; the other two , Arg ẞ ' 1239 and ...
Stran 167
... Substrate loading occurs in two steps . First , the NTP binds to the open EC to form an inactive , preinsertion intermediate , working as a ' ratchet ' that stabilizes the post - translocated EC30 and providing the first sieve for substrate ...
... Substrate loading occurs in two steps . First , the NTP binds to the open EC to form an inactive , preinsertion intermediate , working as a ' ratchet ' that stabilizes the post - translocated EC30 and providing the first sieve for substrate ...
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