and passing all examinations, the successful candidate, will receive the degree of Pharmaceutical Chemist after three years' work, or Bachelor of Pharmacy, after four years' work. Other students who are not candidates for the bachelor's degree, or the pharmaceutical chemist's degree, whether seeking to qualify themselves to serve as examiners under the pure food and drug laws or simply desiring special advanced instruction, will be admitted on giving proof by examination or otherwise of their fitness to take up the work with advantage to themselves and with credit to the college. Provision has been made for those who may wish to take these courses but have not acquired the knowledge and technique of advanced pharmacy, analytical chemistry, and microscopy, which are needed to pursue profitably the line of study required. Such persons will be required to do preliminary work in order to fit themselves for the courses. On satisfactorily completing the course or courses, they will receive certificates of record. PHARMACY AND CHEMISTRY THIRD YEAR Advanced Pharmacy. NISH This course is offered with the idea of qualifying students for the more highly technical processes involved in drug assaying and the standardization of pharmaceutical preparations. It includes the following estimations: the per cent of alcohol and of extractive in samples of galenicals; the per cent of iodine in the official and proprietary preparations containing iodine; the per cent of arsenic in the official and proprietary preparations containing arsenic; the digestive power of samples of pepsin and of the various preparations containing pepsin; the digestive power of pancreatin and of the various preparations containing pancreatin; the per cent of available oxygen in samples of Liquor Hydrogenii Dioxidi and other preparations containing hydrogen peroxide. Gasometric estimations are made of several samples of Spiritus Aetheris Nitrosi. The per cent strength of such ointments as sulphur, zinc oxide, mercurial and ammoniated mercury, is ascertained by methods best suited for their estimation. Alkaloidal Assaying.-The assay processes of the Pharmacopoeia and other approved methods are carried out for the valuation of all vegetable drugs and their preparations possible of assay. The student is required to perform individual work, to keep an accurate record of all processes and their results, and to submit the completed record at the end of the course. This record shall constitute a report of the year's work in pharmacy. Chemistry: Analytical and Applied. GREEN This course is a continuation of the senior laboratory work, but in addition to dealing with the chemical examination of drugs and medicinal preparations, it aims to fit pharmacists to become analysts of foods. Fixed oils, fats, and waxes are analyzed according to the U. S. P. methods, and also by the Official and Tentative Methods of Analysis of the Association of Agricultural Chemists. Essential oils are assayed and tested by the U. S. P. methods. The spectroscope is used in the recognition and study of the alkalies and alkali-earths. Also the absorption spectra of colors are observed. Refractometric observations are made by means of the Abbe and the immersion refractometer. Water analysis from its sanitary and medicinal aspect is taught. Attention is given to the chemistry of the sugars, including the gravimetric and polarimetric methods in use. Toxicology, embracing the study of the inorganic, volatile, and organic poisons, receives the student's attention in the latter part of the course. The course includes a study of the chemistry of the urine, with the qualitative and quantitative estimations of its constituents, both normal and pathologic. The period of study parallels the other chemical laboratory courses, with extensions. MICRO-ANALYSIS AND BACTERIOLOGY Histology of Foods and Drugs. CAREY This course will consist of a microscopical examination of food products and drugs and their more common adulterants. Its aim is to prepare the student to meet the demands of the pure food and drug laws. It will conform as nearly as possible with the methods of study and investigation recommended by the United States Department of Agriculture. Bacteriology. CAREY This course consists of laboratory work, including the preparation of culture media, culture methods, and methods of staining; the culture, examination, and identification of some of the more common microbes of earth, air, and water; a study of pathogenic bacteria and of toxins, antitoxins and microbic products generally. Furthermore, each student is assigned some special work, as the study of the microbic contaminations of pharmaceutical preparations, of water, of food, etc. There are occasional seminar meetings for the purpose of reading papers, comparing notes, and reporting progress. PHARMACY AND CHEMISTRY Advanced Pharmacy. NISH 1. The preparation and purification of inorganic chemical compounds.The mineral deposits in the states west of the Rocky Mountains furnish an abundant source for some of the most interesting and valuable inorganic salts. The salts of potassium, sodium, lithium, ammonium, magnesium, calcium, aluminum, chromium, boron, zinc, manganese, iron, silver, mercury, sulphur, and arsenic offer an attractive list from which the student can make a selection for this particular line of work. 2. The preparation and purification of organic compounds. Such organic acids as acetic, citric, and tartaric are produced from the crude materials which are quite easily obtained, particularly the latter two, owing to the cultivation of the citrus fruit and of the vine in California. Ether, chloroform, chloral, thymol, iodine, iodoform, terpin, hydrate, ethyl nitrite, ethyl acetate, and a number of other organic compounds are prepared in the laboratory. 3. The preparation of compressed tablets, hypodermic tablets, ampules, toilet creams, dental creams, mulls, pastes, etc.-Each student is required to submit formulas, to prepare and to present in a marketable form these and a number of similar pharmaceutical and commercial products. 4. The preparation of diagnostical reagents for clinical tests. Such diagnostical reagents as may be required in the Department are prepared in the pharmacy laboratory. 5. Sterilization.-Special attention is given to the subject of sterilization. This work is performed in connection with that presented in the other branches. The student is required to maintain individual work, to keep an accurate record of all processes and their results, and to submit the completed record at the end of the course. This record shall constitute a report of the year's work in pharmacy. Pharmaceutical Analysis. GREEN The purpose of this course is to train the student in the study of chemical control. The preparations manufactured in the advanced pharmaceutical course will be analyzed not alone for their normal constituents, but their impurities will be estimated as well. It is designed also to familiarize the student with the analysis of toilet requisites, such as face, shaving, and massage creams and lotions; face, bath, and tooth powders, also washes and pastes; hair preparations, such as dressings, depilatories, the so-called tonics, dyes, stains and bleaches, also shampoos. Attention will be given to dermatological and massage preparations, also to the analysis of various remedies and galenical compounds. The practice of pharmaceutical analysis as applied to toilet preparations and remedies lacks completion as far as written or published knowledge is concerned. Much remains undeveloped in this branch of analytical chemistry. The course is offered as an aid to the pharmacist who has a trend toward chemistry, yet desires to pursue pharmacy with as little digression as possible. MICRO-ANALYSIS, MICROBIOLOGY, AND HYGIENE FIRST HALF-YEAR I. Micro-Analysis.—A laboratory course in the microscopical examination of foods and drugs. Textbooks: Winton, Microscopy of Foods; Schneider, Powdered Vegetable Drugs. II. Laboratory Bacteriology.-The bacteriological examination of foods and drugs, including the standardization of disinfectants. Textbook: Schneider, Bacteriological Methods in Foods and Drugs Laboratories. III. General Microbiology.—This is a lecture courrse and is a continuation of the lecture on pharmaceutical bacteriology given during the second year of the regular two-years' course in pharmacy. Special attention will be given to zymology, immunology, and serology. Textbook: Pittfield, A Compend of Bacteriology. IV. General and Special Biology.-A course of lectures and recitations supplemented by laboratory exercises, giving special attention to those organisms concerned in the dissemination of disease. Textbook: Hamaker, The Principles of Biology. SECOND HALF-YEAR CAREY I. Micro-analysis.-Course begun in the first semester continued. II. Laboratory Bacteriology.-Course begun in the first semester continued. III. Public Health and Hygiene.—A lecture course supplemented by recitations and special reading. Textbook: Price and Pedersen, Hygiene and Public Health. IV. Parasitology. This course is supplementary to course (IV) of the first semester. Textbook: Terms, Parasitology. V. Biochemic Assay of Drugs.-A study of the methods employed. Textbook: Pittinger or Jackson, Biochemic Drug Assay Methods. Detailed outlines of the above courses are on file. Students are required to consult special reference works, public health reports, special bulletins and monographs which will be supplied. Each student will be required to present a full report on all samples examined and analyzed at the close of the year's work. He is also required to present at least one report of some special laboratory work representing independent research intended to indicate his ability as an efficient analyst in technical laboratories where work of a similar nature is done. The minimum time required for the work as above outlined is ten hours each week, extending throughout the entire college year. EPITOME OF COURSES WITH TIME AND UNIT VALUES Chemistry. 4 hrs. lectures and recitations; 9 hours. laboratory per week. Tuesday, 8-12, GREEN. Wednesday, 8-12, GREEN. Friday, 8-12, GREEN. Saturday, 10-11, GREEN. First semester, first half-year. 8 units. Total hours, 208. Pharmacy. 4 hrs. lectures and recitations; 12 hrs. laboratory. Tuesday, 8-12, NISH. Wednesday, 8-12, NISH. Thursday, 8-12, NISH. Friday, 8-12, NISH. First semester, second half-year. 8 units. Total hours, 256. Botany. 3 hrs. lecture and recitation; 2 hrs. laboratory per week. Monday, 8-12, CAREY. Saturday, 11-12, CAREY. Throughout the year. 4 units each half-year. Total hours, each halfyear, 80.. Physiology. 1 hr. lecture and recitation per week. Thursday, 11-12, CAREY. Throughout the year. 1 unit each half-year. Total hours, each halfyear, 16. |